The present study was performed to investigate the effects of using chicken abattoir waste powder instead of fish powder using dietary supplement (garlic powder) in the diet of Huso huso with an average initial weight of 50.66 ± 1.5 g, on the index. Growth, carcass composition and digestibility were examined in a completely randomized design with 8 treatments, each with 3 replications for 12 weeks. The treatments included four levels of replacement of fish meal with chicken abattoir waste powder (0, 50, 75 and 100%) and application of two levels of garlic powder (0 and 2%). G: 2% garlic, PG treatment 50: 50% waste + 2% garlic, G treatment 50: 50% waste, PG treatment 75: 75% waste + 2% garlic, G treatment 75: 75% waste, PG treatment 100: 100% Lesions + 2% garlic and G 100 treatment: 100% lesions were named. Treatments containing garlic powder showed a significant increase in weight gain percentage, daily growth and specific growth coefficient compared to treatments without garlic powder. With increasing the level of waste replacement, liver index increased significantly so that the highest liver index was related to 100% waste replacement treatments (100G and 100PG) which showed a significant difference with other experimental treatments (p <0.05). The feed conversion ratio in G treatment had the lowest rate which showed a significant difference compared to other treatments (p <0.05). The results of the main and interaction effects of garlic powder and replacement of chicken slaughterhouse waste showed that their interaction did not cause a significant difference between treatments except in feed conversion ratio index (p> 0.05). The use of garlic did not cause a significant difference in the amount of carcass composition (p> 0.05). However, replacement of the lesions caused a significant difference in the amount of carcass composition (p <0.05). With increasing levels of waste replacement with or without garlic in the diet, a significant decrease in protein digestibility has been observed. But fat digestibility was improved by adding garlic. According to the results, it can be said that the replacement of chicken slaughterhouse waste up to 50% in the elephant fish diet did not have destructive effects. And with the addition of 2% garlic powder, the studied indices improved, but the use of higher levels had adverse effects on some factors.